Does ketoconazole shampoo help hair loss?

Ketoconazole is an antifungal used in shampoos (often 1% over the counter in some countries, 2% by prescription in others). It reduces Malassezia yeast and scalp inflammation, which is why it helps dandruff and seborrheic dermatitis. For androgenetic hair loss, interest comes from anti-inflammatory effects and a possible mild anti-androgen action at the follicle. The clinical literature is small and not in the same league as FDA-approved minoxidil or finasteride. Using it two to three times a week as a lather-and-leave-on-the-scalp wash is a common routine; daily harsh use can dry hair shafts even if the scalp feels cleaner.

If your main problem is greasy scale, itch, and redness, treating that condition can make hair look thicker because less hair is coated and broken. That is not the same as reversing miniaturisation. Brand names vary by country; the ingredient and strength matter more than marketing that says ‘hair growth shampoo.’ People who are pregnant should ask a clinician or pharmacist before using medicated shampoos, especially prescription-strength products. Pair ketoconazole with proven therapy when the diagnosis is pattern loss, and see a dermatologist if scale is thick, painful, or leaving bald patches. This is not medical advice.

出典: AGA review (CCID) ↗

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